Opioid Use
Research Study
Yale University researchers are studying the effects of opioids on the brain using imaging techniques.
Conducted in Yale University, Connecticut Mental Health Center, New Haven, CT
currently using opioids
21 - 55 Years Old
Fast Facts
Study Background
Did you know that over 70 million Americans use opioids for non-medical purposes?

Our team is studying the effect of opioids on the brain using brain imaging. We are inviting people who use opioids to participate in this study.

If you choose to participate in our study, you will be asked to be abstinent from opioids and you have the option to do so in our inpatient unit. You will undergo brain PET scans before and after abstinence. Compensation is provided.
Additional Information
Why is this study being done?
Our researchers want to learn more about how opioid use affects the brain.
Is this study for me?
You may qualify to participate in this study if you meet the following criteria.

Key Criteria:
  • Age 21-55 years
  • Using opioids within the last 3 months
  • Have used opioids for more than 1 year
What will happen if I participate in this study?
If you're potentially eligible, you will be invited to a screening visit where we will conduct a physical examination, psychiatric interview, blood draw, test TSH levels, pregnancy test (if needed), an electrocardiogram, and a urine sample.

Once eligibility is confirmed, you will be contacted and scheduled for inpatient admission to the Clinical Neuroscience Research Unit (CNRU). You will reside in the CNRU for up to 6 weeks to help you detoxify from opioids (up to 2 weeks) followed by participation in experimental procedures, and monitoring/verification of abstinence from drug use.
Will I be paid for being in this research study?
Compensation up to $1400 is provided for your participation in our study.
Will it cost me anything to participate in this study?
There is no cost for you to participate in our research program.