Compensated Smoking Research Study
Researchers at University of Pennsylvania are conducting a research study to learn more about how smoking affects inflammation in the brain.
Able to complete 1 MRI and 2 full day PET/CT scan visits
Compensation for full participation = $830
Smoke Cigarettes Daily
In Generally Good Health
18 - 65 Years Old
Fast Facts
Study Background
The purpose of our research is to examine how smoking can affect specific receptors in the brain. This is not a treatment study and does not involve any counseling or medication to help you quit smoking.

Help researchers learn more about how nicotine affects the brain of cigarette smokers.

Additional Information
Why is this study being done?
The goal of this research study is to learn more about how smoking affects inflammation in the brain.
Is this study for me?
You may qualify for this study if you meet the following criteria.

Key Criteria:
  • Participants are 18-65 years of age
  • Current cigarette smoking for at least the past 6 months
  • Willing to abstain from smoking 24-48 hours before PET scans and complete 1 overnight hospital stay
  • Able to complete 4 study visits, including 1 MRI scan and 2 full day PET/CT scans
What will happen if I participate in the study?
  1. Screening/intake session. This is when we confirm the study is a good fit for you. The visit involves a urine drug screen, completing questionnaires and assessments, and an hour long medical exam by a nurse practitioner (which includes a blood draw).
  2. Brain MRI scan. This visit involves a 1 hour MRI scan.
  3. PET/CT scan 1. This visit lasts 8 hours and involves receiving a PET scan, having an IV placed in each arm, and completing assessments.
  4. PET/CT scan 2. This visit is the same as the first PET scan, but involves an overnight stay in the hospital the day before your scan.
Will I be paid for being in this research study?
Participants will receive up to $830 for completing all study visits.
Will it cost me anything to participate in this study?
There will be no cost to participate in this research program.