Brain Imaging
Research Study
Research study involving state-of-the-art brain imaging at Stony Brook University Medical Center
Stony Brook, NY
Compensation Provided
Chronic Depression
Free Outpatient Treatment
18 - 65 Years Old
Fast Facts
About this research study:
Treating depression using an FDA-approved* anti-inflammatory (nonsteroidal anti- inflammatory drug, NSAID)
The Department of Psychiatry at Stony Brook University is one of the region's premier providers of psychiatric services and a national leader in neuroimaging research. The study involves Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) imaging of the brain. PET and MRI brain imaging is performed before and after 8 weeks of NSAID treatment. This medication is FDA approved as an anti-inflammatory and may be effective to treat depression, especially if other treatments have failed. Your participation in this research study may help further our understanding of depression and other psychiatric illnesses.

*Please note: This medication is currently FDA approved as an anti-inflammatory, not as an antidepressant medication.
Additional Information
Why is this study being done?
According to the World Health Organization, depression will be the 2 nd leading cause of
disability this year. Depression is a common, painful and disabling disorder. Your participation in this research study may help further our understanding of depression and other psychiatric illnesses.
Is this study for me?
Adults between 18 and 65 years old who are currently depressed are eligible.
    How long would I take part in this research?
    The study provides 8 weeks of free outpatient treatment with a medication that reduces inflammation (nonsteroidal anti-inflammatory drug, NSAID). Brain imaging will be performed before and after treatment to learn more about the relationship between depression and inflammation.
    What will happen if I participate in the study?
    The study involves Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) imaging of the brain. PET and MRI brain imaging is performed before and after 8 weeks of NSAID treatment. This medication is FDA approved as an anti-inflammatory and may be effective to treat depression, especially if other treatments have failed. During treatment, you will be provided with free clinical appointments. Throughout the study, you will be interviewed about your physical and emotional health.
    Will I be paid for being in this research study?
    You will be given up to $480 for completing the study.

    You will receive free outpatient medication and a comprehensive medical and
    psychological evaluation during the study.
    Will it cost me anything to participate in this study?
    There will be no cost to you to participate in the study.