Researchers at the Johns Hopkins School of Medicine are looking for healthy volunteers to participate in research studies examining sleep, pain, and medication responses. The studies involve 1 phone screen, 2 in-person screening visits at Johns Hopkins Bayview Campus, and several overnight stays at our clinical research unit. The study may involve experimental sleep deprivation and administration of an FDA approved pain medication and/or placebo. All study sessions, parking, and transportation provided at no cost. Compensation up to $1205 for those who are eligible and complete all aspects of the study.