The first step is to complete this 30 minute phone interview during which we would ask you some questions about your mental and physical health history. If eligible, we would invite you into our office for a full screening assessment, where we will determine your eligibility and explain the details of the study.
Once you are eligible and enrolled, you will complete 2 experimental days. The first day involves an electric shock to your foot that is for most people annoying but not painful. The purpose of the electric shock is to create a situation in which emotional learning may occur. You will receive no more than twelve of these electric shocks. This visit also includes a blood draw to measure the
level of estradiol in your body. On the second day, which takes place the day after the first
visit, you will return to our facilities and we will ask you to do a similar experiment as the first day but inside of our fMRI scanner. Following this 2-day visit, you will go through 6 Prolonged Exposure therapy sessions over 3 weeks: 2 sessions per week. After that, we will repeat the experimental visits over 2-days.