The purpose of this study is to see the short-term and long-term effects of two experimental drugs on alcohol use disorder and post-traumatic stress disorder.

You could be included in the study if you meet the following criteria.

Criteria:

• Males and females aged 18-70 years old
• Are currently experiencing symptoms of traumatic stress
• Have a desire to cut down or stop drinking
• At least 4 heavy drinking days (4 or more drinks per day for a woman, 5 or more drinks per day for a man) in the 30 days prior to screen
• If of childbearing potential (male or female), willing to use contraception for the duration of the trial
• Agrees to abstain from all other cannabinoid use for the duration of the study

If you agree to participate in one of our studies, the first visit will be a screening visit. The screening visit can be done in-person, or over the phone or video call. The purpose of the screening visit is to make sure that you meet all of the conditions to participate in the study and that it is safe for you to take the study drug. The screening visit includes reviewing and signing informed consent forms, a contact sheet, alcohol use and psychiatric assessments, and medical and family history. This first visit will take approximately 2 - 5.5 hours.

If you are eligible after the first visit, you will be asked to come in for a shorter, in-person medical and physical screen to confirm your eligibility. Then, you will participate in a series of procedures over the course of 9 to 14 assessment visits. Depending on the study you are eligible for, these procedures may differ. Participation will span 12-14 weeks, depending on the study you’re enrolled in, and will typically require one visit a week where you will come to our offices.

Compensation is provided for participation in this study.

There is no cost for you to participate in the study.