Compensated Zika Virus Research Study
The Johns Hopkins CIR research team is conducting a challenge study to test two strains of Zika virus (ZIKV) that can be used for future vaccine studies.
Compensation Provided
18-40 Years Old
9-day Inpatient
Conducted in Baltimore, MD
Generally Healthy Men
Fast Facts
Study Background
Participate in a compensated research study that will help Johns Hopkins researchers find a new vaccine to prevent the Zika Virus.
Zika is a virus spread by Aedes mosquitoes. The Zika virus infection is dangerous during pregnancy and can cause various disabilities in infants.
By taking part in our research study, you can assist us in developing a vaccine to prevent the Zika virus and earn up to $5,175 in compensation.
Zika is a virus spread by Aedes mosquitoes. The Zika virus infection is dangerous during pregnancy and can cause various disabilities in infants.
By taking part in our research study, you can assist us in developing a vaccine to prevent the Zika virus and earn up to $5,175 in compensation.
Additional Information
Our study aims to learn more about the effects of the Zika virus in people. We hope to identify a strain of the Zika virus that can be used in future vaccine studies.
You may qualify for this study if you meet the following criteria.
Inclusion Criteria:
Inclusion Criteria:
- Healthy men
- 18–40 years old
- Available for 6 months to complete an inpatient stay and follow-up visits
- Never received a flavivirus vaccine (i.e., yellow fever)
- Men who are capable of fathering a child MUST be willing to use barrier birth control and not planning to father a child within 6 months of enrollment
- Impaired immunity (i.e. MS, History of Cancer, Lupus, or use of steroids)
Before entering the study, there will be at least 2 in-person screening visits. We will collect blood and urine tests to see if you are healthy. We will also check to see if you have had any previous exposure to mosquito-borne diseases.
If you are eligible, you will then have a 9-day inpatient stay and 13 follow-up visits, as well as one follow-up phone call.
During our study, we will frequently check you for side effects and illness. We will check your blood, urine, and saliva for ZIKV.
We will also study how your immune system responds to receiving a shot of one of the two strains of ZIKV. To do this, we will measure the disease-fighting cells (antibodies) in your blood and collect different blood cells. We will also collect a sample from your mouth with an oral swab.
If you are eligible, you will then have a 9-day inpatient stay and 13 follow-up visits, as well as one follow-up phone call.
During our study, we will frequently check you for side effects and illness. We will check your blood, urine, and saliva for ZIKV.
We will also study how your immune system responds to receiving a shot of one of the two strains of ZIKV. To do this, we will measure the disease-fighting cells (antibodies) in your blood and collect different blood cells. We will also collect a sample from your mouth with an oral swab.
You will be compensated up to $5,175 for your participation.
There will be no cost to participate in our research study.