Compensated Zika Virus Research Study
The Johns Hopkins CIR research team is conducting a challenge study to test two strains of Zika virus (ZIKV) that can be used for future vaccine studies.
Compensation Provided
18-40 Years Old
16-day Inpatient
Conducted in Baltimore, MD
Healthy Women
On Birth Control
Fast Facts
Study Background
Participate in a compensated research study that will help Johns Hopkins researchers find a new vaccine to prevent the Zika Virus.

Zika is a virus spread by Aedes mosquitoes. The Zika virus infection is dangerous during pregnancy and can cause various disabilities in infants.

By taking part in our research study, you can assist us in developing a vaccine to prevent the Zika virus and earn up to $5,025 in compensation.
Additional Information
Why is this study being done?
Our study aims to learn more about the effects of the Zika virus in people. We hope to identify a strain of the Zika virus that can be used in future vaccine studies.
Is this study for me?
You may qualify for this study if you meet the following criteria.

Inclusion Criteria:
  • Healthy women
  • 18–40 years old
  • Currently on effective birth control
  • Available for 6 months to complete an inpatient stay and follow up visits
  • Never received a flavivirus vaccine (i.e., yellow fever)

Exclusion Criteria:
  • Pregnant
  • Breast-feeding women
What will happen if I participate in the study?
Before entering the study, we will collect blood and urine tests to see if you are healthy. We will also check to see if you have had any previous exposure to mosquito-borne diseases.

During our study, we will frequently check you for side effects and illness. We will check your blood, urine, cervical vaginal secretions, and saliva for ZIKV.

We will also study how your immune system responds to receiving a shot of one of the two strains of ZIKV. To do this, we will measure the disease-fighting cells (antibodies) in your blood and collect different blood cells. We will also collect a sample from your mouth with an oral swab.
Will I be paid for being in this research study?
You will be compensated up to $5,525 for your participation.
Will it cost me anything to participate in this study?
There will be no cost to participate in our research study.