Before entering the study, we will collect blood and urine tests to see if you are healthy. We will also check to see if you have had any previous exposure to mosquito-borne diseases.
During our study, we will frequently check you for side effects and illness. We will check your blood, urine, cervical vaginal secretions, and saliva for ZIKV.
We will also study how your immune system responds to receiving a shot of one of the two strains of ZIKV. To do this, we will measure the disease-fighting cells (antibodies) in your blood and collect different blood cells. We will also collect a sample from your mouth with an oral swab.