Opioid Use Disorder
Research Program
Icahn School of Medicine at Mount Sinai is conducting a research study testing how CBD could potentially decrease your craving for opioids
New York, NY
Not on Medication Assisted Treatment
Currently Recovering From Opioid Use Disorder
18 - 65 Years Old
Fast Facts
About this research study:
Join a research study that can potentially help reduce craving and anxiety in people addicted to opioids. The goal of the study is for researchers to understand the neurobiological effects of a cannabidiol (CBD) product.
Over 10 million people in the USA use opioids today. The misuse of opioids has impacted all sociodemographic groups in our nation. Regular treatments are limited and subject to very restrictive regulations. Additionally, they do not effectively treat opioid cravings that might result in high rates of relapse.

Our study will investigate the neurobiological effects of a cannabidiol (CBD) product. This product has the potential to treat opioid use disorder in the future.

Additional Information
Why is this study being done?
Our study will investigate the neurobiological effects of cannabidiol (CBD) to eliminate your cravings for opioids. The goal of this study is to find out the neurobiological mechanisms for CBD's effects and be able to offer it as a treatment more broadly in the future.
Is this study for me?
You may qualify for this study if you meet the following criteria.

Key Criteria:
  • No opioid use in the past 7 days
  • Between the ages of 18 and 65 years old
What will happen if I participate in the study?
If you qualify and agree to participate in this research study, the following information describes what may be involved. You would:
  • Complete 5 site visits that will include an initial screening, administration of the test compound (3 days in a row) and a last visit 1 week after the last drug administration.
  • Undergo a physical exam with measurements of vital signs including heart rate and blood pressure
  • Complete questionnaires about general medical, psychiatric, and substance use history
  • Provide blood and urine samples
  • Attend 2 neuroimaging scanning (MRI) sessions. Both sessions will last approximately 4 hours in which you lie in an MRI scanner.
Will I be paid for being in this research study?
Yes, participants will be compensated.
Will it cost me anything to participate in this study?
There is no cost for the study medicine or study tests.