Opioid Brain Imaging Research Study
Stony Brook University is helping people who take opioids understand how the brain affects thoughts and behaviors.
Stony Brook University Medical Center, located in Stony Brook, NY
Compensation Provided
Current Opioid User OR On Medication Treatment
18 - 55 Years Old
Fast Facts
About this research study:
The purpose of this study is to better understand thinking and decision-making in opioid addiction.
How people think about themselves and their actions may play an important role in opioid addiction and its treatment. We are studying self-focused thinking in opioid addiction and the brain circuits that are involved with this kind of thinking. We are also interested in whether thinking and brain patterns are linked to drug use and treatment success. Active users and those on opioid medications are eligible.

Additional Information
Why is this study being done?
Long-term use of opioids changes how the brain and body work, and these changes can affect your actions and thoughts. Changes in your actions and thoughts may lead to more drug use, which then leads to more changes to your brain and body. This cycle is likely to make the addiction worse over time and make treatment and sobriety more difficult to achieve. We are trying to better understand this cycle so that we can develop new and better treatment options in the future. Active users and those on opioid medications are eligible. The research is done in person at Stony Brook University Medical Center located in Stony Brook, NY.
Is this study for me?
Inclusion criteria:
  • Ages 18-55
  • Fluent in English
  • Current opioid use disorder and/or currently taking medication-assisted treatment for opioid use disorder
  • Right-handed, for MRI

Exclusion criteria:
  • Major medical or neurological illness that interferes with your daily activites
  • If you use other drugs besides opioids or cannabis
  • Pregnancy or breast-feeding in women
  • Metal in your head, mouth, or neck area, for brain MRI
What will happen if I participate in the study?
The research involves several activities.

  • Surveys and questionnaires
  • Medical physical exam, including blood draw
  • Confidential clinical interviews
  • Cognitive & behavioral testing
  • One or more MRI scans of your brain
  • Two more laboratory sessions between MRI days
  • Computer tasks, including during MRI
  • Urine screenings
Will I be paid for being in this research study?
You can expect to be paid between $100 and $440. You may be paid less or more than this, depending on which pieces of the research you sign up for and how long you are part of it. Payment is by the hour. Brain imaging is paid at a higher rate. The study team will give you full information.
Will it cost me anything to participate in this study?
There is no cost for you to participate in the study.